News · Latest treatments

Walk in informed.

Treatment news lands as press releases and jargon. We translate it: what's approved, what's coming, and the questions worth raising with your neurologist — with every source one click away.

Nothing here is a recommendation. Treatment decisions are deeply individual — this page exists so you can bring better questions to the people who know your history.

Hand-curated · updated July 2026 · every card links to its original source

BTK inhibitors

Tolebrutinib: the first therapy aimed at smouldering progression

Tolebrutinib crosses the blood-brain barrier to calm the slow-burn inflammation behind disability progression. In the HERCULES trial it delayed progression by 31% in non-relapsing secondary progressive MS. Approved in Europe; the US FDA has asked for more information, with guidance expected during 2026.

NeurologyLive · Sanofi HERCULES trial2026
Long-term data

Ocrevus Zunovo: 96.7% relapse-free at 96 weeks

The newer subcutaneous form of ocrelizumab — a ten-minute injection instead of an infusion — kept 96.7% of people relapse-free across 96 weeks, making high-efficacy treatment lighter to live with.

MSAA research roundupMay 2026
Cell therapy

CAR-T therapy enters MS trials

The cell therapies that transformed blood cancer are now being tested in MS. KYV-101 has FDA clearance for a phase 2 trial in refractory progressive MS, with several other candidates (IMPT-514, AZD0120) entering early trials. Experimental — and genuinely new territory.

NeurologyLive · clinicaltrials.gov2025–26
Established options

The bigger picture: more high-efficacy options than ever

Stepping back: today's landscape spans more than twenty disease-modifying therapies, with growing evidence for starting high-efficacy treatment early. If your current therapy was chosen years ago, it may be worth a fresh conversation.

New Horizons for MS Therapy — peer-reviewed review2025
Worth knowing

Where we watch from, month to month

For rolling updates between our curation passes, MSAA's monthly "What's New in MS Research" is the steadiest, least sensational digest we know. It's where several of this page's stories were first gathered.

Multiple Sclerosis Association of AmericaMonthly
A gentle reminder about timelines: "in trials" usually means years away, and not every promising result survives phase 3. We include early-stage news because hope with sources attached is still hope — just hold it lightly.